When was the last time you felt like you were in
total control over your business?

Wouldn’t it be great to have a “second set of eyes” on your business -
designed by owners for owners like you?


We’re partnering with Restaurant Owners who want to better manage their bottom line and reduce the inherent risks of running a restaurant.


We're engaging Doctors and Dentists who are concerned about how rising costs and regulatory compliance threatens their ability to remain independent.


We're teaming up with Builders and Contractors who want to better understand how an unpredictable market with increasing sub-contractor complexity is impacting their business.

Jeff Reid
"Main Street Genome is a great example of how the Georgetown University Entrepreneurship Initiative bridges the gap between the University and the startup community."
Jeff Reid | Georgetown Entrepreneurship Initiative

Tonic Restaurant
"Dollars and cents fall through the cracks at restaurants every day. Over the course of the year, this results in tens of thousands of dollars of lost income. No owner is immune to this problem, and that's what Main Street Genome is working on...protecting my income by helping me identify risks that are harming my business."
Jeremy Pollok | Owner of Tonic Restaurants

Our Team

We are a team of entrepreneurs, business owners, technologists, developers, and data analysts passionate about taking the risk out of running your business.

1627 K Street NW, Suite 600, Washington, DC, 20006 | 202.306.9011 | info@mainstreetgenome.com

©2015 Main Street Genome. All Rights Reserved. | Privacy Policy
Main Street Genome Inc BBB Business Review